It is believed the victim, aged in his 30s, may have been involved in a fight shortly before he was stabbed in Warwick Road, Forest Gate.
Paramedics treated the victim and took him to hospital, where he sadly died.
His next of kin has not yet been informed and his body has not yet been formally identified.
Metropolitan Police said in a statement: “Officers were called to Warwick Road, E15 to reports that a fight was taking place.
“No arrests have been made at this time”
“The victim, a man in his 30s, was found suffering from stab injuries.
“He was taken to hospital by LAS where he sadly died.
“Officers are working to inform his next of kin. Formal identification awaits.
“A post-mortem examination will be held in due course.
“No arrests have been made at this time.
“The Homicide and Major Crime Command have been informed.
“Enquiries into the circumstances continue.”
Anyone with information is asked to contact police on 101 quoting CAD427/28May. Information can also be passed 100% anonymously to Crimestoppers via 0800 555 111.
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