Fans have previously raised $60,000 in honour of Meghan’s son Archie Harrison Mountbatten Windsor and look to repeat the gesture for Ms Markle’s upcoming birthday.
The former Duchess of Sussex turns 39 on August 4 and fans seek to celebrate the occasions with donations through social media.
‘The Sussex Squad’ took to Twitter to reach out to other supporters and look to arrange further donations using the Twitter account @HBDDuchess.
The account posted: “To celebrate the 39th birthday of Meghan The Duchess of Sussex, several members of the Sussex Squad have organised a fundraising campaign.
“We are no strangers to fundraising celebrations, and we are very proud of the organisations we have chosen.”
They described the event as a “Virtual Fundraising Birthday party for Meghan the Duchess of Sussex. July 22-August 4 #HappyBirthdayDuchessMeghan.”
Dani Trin, a university student, created a similar initiative to celebrate Archie’s birthday last month and she raised $60,000 for a collection of charities.
Her efforts didn’t go unnoticed by Meghan, who alongside her husband, Prince Harry treated Miss Trin to a personal call.
Speaking to Bazaar.com at the time, Trin said: “We never had a specific amount we hoped to hit.
“Ultimately, we hoped to simply help the charities and raise awareness for the projects people are conducting to help children through this pandemic.”
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“A once abandoned farm in upstate New York is now the home of #ArchiesWoods.”
The Duchess celebrated Archie’s birthday by reading one of her son’s favourite books, Duck! Rabbit! By Amy Krouse Rosenthal.
Meghan recorded the event as part of the Save With Stories campaign, run by UK charity Save the Children.
The glowing video saw the Duchess refer to her child as “Arch”, whilst Prince Harry’s son attempts to say “da” on numerous occasions.
Meghan starts the video by saying: “For Save With Stories we’re going to read Duck! Rabbit! Good job.”
Speaking at the time, a spokesperson for The Duke and Duchess said: “As they celebrate this family moment, the duke and duchess wanted to continue to raise awareness around the urgency of bringing food and learning resources to millions of children.
“The duchess chose to read one of Archie’s favourite stories, Duck! Rabbit!”