Former heavyweight champ Iron Mike got involved in the apparent punch-up during a podcast record.
Surprisingly, it was Wack100 who reportedly threw the first punch.
Wack had sparked controversy by posting a pic on Instagram that seemed to question murdered rap star Tupac’s sexuality.
He shared an image of Tupac lying in bed with a man who is resting his head on him.
“Just know this Wack wasn’t giving up s*** and Mike still quick with his hands”
Wack, who manages rapper The Game, was on the HotBoxin podcast with Tyson when it turned ugly.
The music manager later put a pic of Tyson, co-host Eben Britton and himself, on Instagram.
He captioned it: “Just know this Wack wasn’t giving up s*** and Mike still quick with his hands!
“@edsbritton sorry you had to see what you saw but it’s what brothas do when we can’t solve the problem with reason!!”
He also posted a snap of prescription painkillers.
The account of the fight is backed up by an alleged phone call between Wack and hip hop star Reggie Wright Jr.
Wack again suggests he threw the first punch: “You just gonna have to whoop my ass around this mother f***** then and it went the way it went.”
Tyson put up a pic of himself with Tupac up on Instagram in which he included a link to Wack.
He wrote: “Everybody has a plan ‘til they get punched in the mouth. Ain’t that right @wack100.”